منابع مشابه
Liver Fluke Induces Cholangiocarcinoma
Liver fl uke infection caused by Opisthorchis viverrini, O. felineus, and Clonorchis sinensis is a major public health problem in East Asia and Eastern Europe. Currently, more than 600 million people are at risk of infection with these trematodes [1]. O. viverrini is endemic in Southeast Asian countries, including Thailand, Lao People’s Democratic Republic, Vietnam, and Cambodia [2], and C. sin...
متن کاملCholangiocarcinoma Associated with Liver Fluke Infection in an Iranian Patient
Biliary liver flukes are common parasites in some regions of the world where consumption of raw fresh-water fish is a cultural practice. Clonorchis sinensis and Opisthorchis species are the major biliary liver flukes associated with human disease. Some of these parasites are highly associated with cholan...
متن کاملcholangiocarcinoma associated with liver fluke infection in an iranian patient
biliary liver flukes are common parasites in some regions of the world where consumption of raw fresh-water fish is a cultural practice. clonorchis sinensis and opisthorchis species are the major biliary liver flukes associated with human disease. some of these parasites are highly associated with cholangiocarcinoma. this report describes a clinically and epidemiologically unsuspected liver flu...
متن کاملBehavioral Modification Regarding Liver Fluke and Cholangiocarcinoma Using Integrated Learning
Liver fluke infection caused by O. viverrini remains a major public health problem in Thailand particularly Northeastern and Northern region (Kaewpitoon et al., 2008b; Sitthithaworn et al., 2012; Kaewpitoon et al., 2015f). A nationwide survey in Thailand found that the prevalent was 5.1%. The highest of prevalent was found in the northeast (9.2%) and followed by the north region (5.2%) (Wongsar...
متن کاملCD44 variant‐dependent redox status regulation in liver fluke‐associated cholangiocarcinoma: A target for cholangiocarcinoma treatment
Expression of CD44, especially the variant isoforms (CD44v) of this major cancer stem cell marker, contributes to reactive oxygen species (ROS) defense through stabilizing xCT (a cystine-glutamate transporter) and promoting glutathione synthesis. This enhances cancer development and increases chemotherapy resistance. We investigate the role of CD44v in the regulation of the ROS defense system i...
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ژورنال
عنوان ژورنال: PLoS Medicine
سال: 2007
ISSN: 1549-1676
DOI: 10.1371/journal.pmed.0040201